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Meds name / Generic Name:
Abilify Aripiprazole
Aceon Perindopril
Aciphex Rabeprazole
Acomplia Rimonabant
Actonel Risedronate
Actos Pioglitazone
Acuitel Quinapril
Adalat Nifedipine
Albenza Albendazole
Albuterol Salbutamol
Albuterol Salbutamol
Aldactone Spironolactone
Alesse Pruquin
Alesse Levonorgestrel + ethinyl estradiol
Alfacip Alfacalcidol
Allegra Fexofenadine
Allegra Fexofenadine
Alphagan Brimonidine
Altace Ramipril
Altace Ramipril
Amaryl Glimepiride
Amoxicillin Amoxil
Ampicillin Acillin
Anafranil Clomipramine hci
Anaprox Naproxen
Aralen Chloroquine
Arava Leflunomide
Arcoxia Etoricoxib
Aricept Donepezil
Arimidex Anastrozole
Asacol Mesalamine
Atacand Candesartan
Atarax Hydroxyzin
Atorvastatin Lipitor
Atrovent Aerovent
Augmentin Amoxicillin
Avandia Rosiglitazone
Avapro Irbesartan
Avodart Dutasteride
Aygestin Norethindrone acetate
Bactrim Trimethoprim
Bactroban Mupirocin
Beclovent Beclomethasone
Biaxin Clarithromycin
Biaxin+xl Clarithromycin xl
Brethine Terbutaline
Buspar Buspirone
Calan Verapamil
Capoten Captopril
Carafate Sucralfate
Cardarone Amiodarone
Cardizem Diltiazem
Cardura Doxazosin
Casodex Bicalutamide
Catapres Clonidine
Caverta Sildenafil caverta
Ceclor Cefaclor
Ceftin Cefuroxime
Celebrex Celecoxib
Celexa Citalopram
Chantix Varenicline
Chloromycetin Chloramphenicol
Cialis Tadalafil
Cialis+soft Tadalafil soft
Cimetidine Acibilin
Cipro Ciprofloxacin
Clarinex Desloratadine
Claritin Loratadine
Cleocin Clindamycin
Clomid Clomiphene
Colospa Mebeverine
Combivir Lamivudine
Compazine Prochlorperazine
Copegus Ribavirin
Coreg Carvedilol
Coumadin Warfarin
Coversyl Perindopril
Cozaar Losartan
Crestor Rosuvastatin
Cymbalta Duloxetine
Cytoxan Cyclophosphamide
Danocrine Danazol
Ddavp Desmopressin
Ddavp Desmopressin
Deltasone Prednisolone
Demadex Torsemide
Depakote Divalproex
Desyrel Trazodone
Detrol Tolterodine
Diamox Acetazolamide
Diflucan Fluconazole
Dilantin Phenytoin
Dimenhydrinate Dimenhydrin
Diovan Valsartan
Ditropan Oxybutynin
Doxycycline Doxycycline hyclate
Dramamine Dimenhydrinate
Duphaston Dydrogesterone
Duricef Cefadroxil
Effexor Venlafaxine
Elavil Amitriptylin
Eldepryl Selegiline
Elimite Permethrin
Emulgel Dicloflam
Epivir Lamivudine
Estrace Estradiol
Eulexin Flutamide
Evista Raloxifene
Exelon Rivastigmine
Famvir Famciclovir
Feldene Piroxicam
Femara Letrozole
Finpecia Finasteride
Flagyl Metronidazol
Flomax Tamsulosin
Florinef Fludrocortisone
Flovent Fluticasone
Floxin Ofloxacin
Fosamax Alendronate
Frumil Amiloride
Fulvicin Gresiofulvin
Geodon Ziprasidone
Gestanin Allyloestrenol
Glucophage Metformin
Glucotrol Glipizide sr
Grisactin Griseofulvin
Hydrea Hydroxyurea
Hytrin Terazosin
Ilosone Erythromycin
Imdur Isosorbide mononitrate
Imitrex Sumatriptan
Imodium Loperamide
Imuran Azathioprine
Inderal Propranolol
Indocin Indomethacin
Januvia Sitagliptin
Kamagra Sildenafil
Keflex Cephalexin
Lamictal Lamotrigine
Lamisil Terbinafine
Lamisil Terbinafine
Lanoxin Digoxin
Lasix Furosemide
Levaquin Levofloxacin
Levitra Vardenafil
Levlen Levonorgestrel + ethinyl estradiol
Lexapro Escitalopram
Lioresal Baclofen
Lithobid Lithium
Lopid Gemfibrozil
Lopressor Metoprolol
Lotensin Benazepril
Lozol Indapamide
Luvox Fluvoxamine
Maxalt Rizatriptan
Maxolon Metoclopramide
Methotrexate
Mevacor Lovastatin
Micardis Telmisartan
Microzide Hydrochlorothiazide
Minipress Prazosin
Minomycin Minocycline
Mirapex Pramipexol
Mircette Ethinyl estradiol + desogestrel
Mobic Meloxicam
Modalert
Moduretic Amiloride and hydrochlorothiazide
Motilium Domperidone
Motrin Ibuprofen
Myambutol Ethambutol
Mycelex Clotrimazol
Namenda Memantine
Naprosyn Naproxen
Neurontin Gabapentin
Nexium Esomeprazole
Nexium Esomeprazole
Nizoral Ketoconazole
Nizoral Ketoconazole
Nolvadex Tamoxifen
Norvasc Amlodipine
Ortho+tri-cyclen Ethinyl estradiol + norgestimate
Ovral Norgestrel + ethinyl estradiol
Pamelor Nortriptyline
Paracetamol Paracip
Parlodel Bromocriptine
Paxil Paroxetine
Pepcid Famotidine
Periactin Cyproheptadine
Persantine Dipyridamole
Plavix Clopidogrel
Plendil Felodipine
Pletal Cilostazol
Ponstel Mefenamic acid
Prandin Repaglinide
Precose Acarbose
Premarin Estrogens
Premarin Estrogens
Prevacid Lansoprazole
Prilosec Omeprazole
Prilosec Omeprazole
Propecia Finasteride
Proscar Finasteride
Protonix Pantoprazole
Proventil Albuterol
Provera Medroxyprogesterone
Pulmicort Budesonide
Rebetol Ribavirin
Reglan Metoclopramide
Remeron Mirtazapine
Retin-a Tretinoin
Retrovir Zidovudine
Revia Naltrexone
Rifadin Rifampin
Risperdal Risperidone
Robaxin Methocarbamol
Rulide Roxithromycin
Serevent Salmeterol
Sildenafil+citrate
Sildenafil+oral+jelly
Sildenafil+soft+tabs
Sinemet Carbidopa + levodopa
Sinequan Doxepin
Singulair Montelukast
Spiriva Tiotropium
Spiriva Tiotropium
Sporanox Itraconazole
Starlix Nateglinide
Strattera Atomoxetine
Sumycin Tetracycline
Suprax Cefixime
Sustiva Efavirenz
Symmetrel Amantadine
Synthroid Levothyroxine
Tegopen Cloxacillin
Tegretol Carbamazepine
Temovate Clobetasol
Tenoretic Atenolol + chlorthalidone
Tenormin Atenolol
Theo-24 Theophylline
Tofranil Imipramine
Topamax Topiramate
Toprol Metoprolol
Toprol+xl Metroprolol xl
Toprol+xr Metroprolol xr
Tricor Fenofibrate
Trileptal Oxcarbazepine
Tritace Ramipril
Trivastal Piribedil
Urispas Flavoxate
Urso Ursodiol
Valparin Valproic acid
Valtrex Valacyclovir
Vantin Cefpodoxime
Vasotec Enalapril
Voltaren Diclofenac
Wellbutrin Bupropion
Xalatan Latanoprost
Xalatan Latanoprost
Xenical Orlistat
Yasmin Drospirenone / ethynil estradiol
Zanaflex Tizanidine
Zantac Ranitidine
Zebeta Bisoprolol
Zelnorm Tegaserod
Zerit Stavudine
Zestoretic Lisinopril + hydrochlorothiazide
Zestril Lisinopril
Zetia Ezetimibe
Zithromax Azithromycin
Zocor Simcard
Zofran Ondansetron
Zovirax Acyclovir
Zovirax Acyclovir
Zyban Bupropion
Zyloprim Allopurinol
Zyrtec Cetirizine

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What is the most important information I should know about Depakote?

  • In rare cases, Depakote has caused life-threatening liver failure, especially in children younger than 2 years old. Children of this age may be at even greater risk for liver problems if they use more than one seizure medication, if they have a metabolic disorder, or if they have a brain disease causing mental impairment (such as Creutzfeldt-Jacob disease, Huntington disease, multiple sclerosis, or a brain injury or infection).
  • Depakote has also caused rare cases of life-threatening pancreatitis (inflammation of the pancreas). Pancreatitis can come on suddenly and symptoms may start even after you have been taking Depakote for several years.
  • Seek emergency medical attention if the person taking this medicine has nausea, vomiting, stomach pain, or loss of appetite, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). These symptoms may be early signs of liver damage. Some of these symptoms may also be early signs of pancreatitis.
  • Do not use this medication without your doctor's consent if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.
  • Do not stop taking the medication even if you feel better. It is important to take Depakote regularly to prevent seizures from recurring. Call your doctor promptly if this medicine does not seem to be working as well in preventing your seizures.
  • Do not crush, chew, break, or open a delayed-release or extended-release tablet or capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.
  • Carry an ID card or wear a medical alert bracelet stating that you are taking Depakote, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking Depakote.
  • Avoid using other drugs that make you sleepy (such as other seizure medicines, alcohol, cold medicine, pain medication, muscle relaxers, and medicine for depression or anxiety). They can add to sleepiness caused by Depakote.

What is Depakote?

  • Depakote affects chemicals in the body that may be involved in causing seizures.
  • Depakote is used to treat various types of seizure disorders. Depakote is sometimes used together with other seizure medications.
  • Depakote may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Depakote?

  • In rare cases, Depakote has caused life-threatening liver failure, especially in children younger than 2 years old. Children of this age may be at even greater risk for liver problems if they use more than one seizure medication, if they have a metabolic disorder, or if they have a brain disease causing mental impairment (such as Creutzfeldt-Jacob disease, Huntington disease, multiple sclerosis, or a brain injury or infection).
  • Depakote has also caused rare cases of life-threatening pancreatitis (inflammation of the pancreas). Pancreatitis can come on suddenly and symptoms may start even after you have been taking Depakote for several years.
  • Do not take Depakote if you have liver disease or a urea cycle disorder.
  • Before taking Depakote, tell your doctor if you have:
    • a bleeding or blood clotting disorder;
    • a history of head injury, brain disorder, or coma;
    • a family history of a urea cycle disorder;
    • a family history of infant deaths with unknown cause; or
    • HIV or CMV (cytomegalovirus) infection.
  • If you have any of these conditions, you may not be able to use Depakote, or you may need a dosage adjustment or special tests during treatment.
  • FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use Depakote without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication.
  • Depakote passes into breast milk and could harm a nursing infant. Do not take Depakote without telling your doctor if you are breast-feeding a baby.
  • Depakote should not be given to a child younger than 2 years of age without a doctor's consent.
  • Older adults may be more sensitive to sleepiness caused by this medicine.

How should I take Depakote?

  • Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
  • Take each dose with a full glass of water. Drink plenty of water while you are taking this medication. Your dose may need to be changed if you do not get enough fluids each day.
  • To be sure this medication is not causing harmful effects, your liver function will need to be tested. It is important that you not miss any scheduled visits to your doctor.
  • Do not stop taking the medication even if you feel better. It is important to take Depakote regularly to prevent seizures from recurring. Get your prescription refilled before you run out of medicine completely. Call your doctor promptly if this medicine does not seem to be working as well in preventing your seizures.
  • Do not crush, chew, break, or open a delayed-release or extended-release tablet or capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.
  • Carry an ID card or wear a medical alert bracelet stating that you are taking Depakote, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are taking Depakote.
  • Store Depakote at room temperature away from moisture and heat.

What happens if I miss a dose?

  • Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

  • Seek emergency medical attention if you think you have used too much of this medicine.
  • Symptoms of a Depakote overdose may include sleepiness or drowsiness, shallow breathing, weak pulse, or loss of consciousness.

What should I avoid while taking Depakote?

  • Avoid drinking alcohol, which can increase some of the side effects of Depakote.
  • Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by Depakote.
  • Depakote can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
  • Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Depakote can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

What are the possible side effects of Depakote?

  • Seek emergency medical attention if the person taking this medicine has nausea, vomiting, stomach pain, or loss of appetite, low fever, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). These symptoms may be early signs of liver damage. Some of these symptoms may also be early signs of pancreatitis.
  • Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
  • Call your doctor at once if you have any of these serious side effects:
    • unexplained weakness with vomiting and confusion or fainting;
    • easy bruising or bleeding, unusual weakness;
    • fever, skin rash, swollen glands;
    • fever, chills, body aches, flu symptoms;
    • urinating less than usual;
    • blood in your urine;
    • hallucinations (seeing things that aren't there);
    • weakness, lack of coordination;
    • a red, blistering, peeling skin rash;
    • extreme drowsiness;
    • unusual bleeding or bruising; or
    • double vision or back-and-forth movements of the eyes.
  • Continue using Depakote and talk with your doctor if you have any of these less serious side effects:
    • drowsiness or weakness;
    • diarrhea, constipation, upset stomach;
    • depression, anxiety, or other emotional changes;
    • changes in your menstrual periods;
    • enlarged breasts;
    • tremor (shaking);
    • hair loss;
    • weight changes;
    • a red, blistering, peeling skin rash;
    • vision changes; or
    • unusual or unpleasant taste in your mouth.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Depakote?

  • Before taking Depakote, tell your doctor if you are using any of the following drugs:
    • topiramate (Topamax);
    • tolbutamide (Orinase);
    • a blood thinner such as warfarin (Coumadin);
    • aspirin or acetaminophen (Tylenol);
    • zidovudine (Retrovir);
    • clozapine (Clozaril, Fazaclo);
    • diazepam (Valium);
    • meropenem (Merrem);
    • rifampin (Rifadin, Rimactane, Rifater);
    • ethosuximide (Zarontin); or
    • another seizure medicine such as phenytoin (Dilantin), carbamazepine (Tegretol, Carbatrol), phenobarbital (Luminal, Solfoton), felbamate (Felbatol), lamotrigine (Lamictal), or clonazepam (Klonopin).
  • If you are using any of these drugs, you may not be able to use Depakote, or you may need dosage adjustments or special tests during treatment.
  • There may be other drugs not listed that can affect Depakote. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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